Metrics details. It has recently been reported that intermittent fasting shapes the gut microbiota to benefit health, but this effect may be influenced to the exact fasting protocols. The purpose of this study was to assess the effects of different daily fasting hours on shaping the gut microbiota in mice. Gut microbiota was analyzed by 16S rRNA gene-based sequencing and food intake was recorded as well. The composition of gut microbiota was altered by all these types of intermittent fasting. No taxonomic differences were identified in the other two groups. These data indicated that intermittent fasting shapes gut microbiota in healthy mice, and the length of daily fasting interval may influence the outcome of intermittent fasting. Gut microbiota consists of a group of microorganisms that live in the mammalian intestinal tract and plays key roles in health and disease. Gut microbiota is not only involved in a number of major physiological processes including fermentation of indigestible dietary polysaccharides and synthesis of essential amino acids and vitamins, but also is a vital factor in maintaining gut homeostasis for host [ 1 ].
Consent for publication Not applicable. You may hear recommendations to increase your fasting window to sixteen-plus hours, but although this works well for some individuals, it may not be best for everyone. The concept is that with intermittent fasting, you could permanently grow those bacteria and experience the associated benefits. After the study, all mice were killed by cervical dislocation and subsequently treated as non-hazardous waste. And they found that flies that fasted and activated that brain-gut signal lived twice as long as their less fortunate counterparts. To help you get started, here are a few of the most popular I. A great number of studies have provided evidence for health benefits of intermittent fasting to host [ 4, 5, 6 ]. Alternate-day fasting is not recommended as a long-term regimen. Albrecht U. J Transplant.
Discussion Fasting, in particular intermittent and timing fasting, is being widely practiced for various purposes in global population, for at least millennia now. With intermittent fasting, one of the reasons it works so well for weight loss is because you introduce this caloric deficit during your week that’s pretty profound, but your body never switches into starvation mode because the next day you’re eating normally. Ingredient Spotlight. We also studied healthy humans to look at the gut microbiome to see how it changes with 2 fasts per week. Zarrinpar, Amir, et al. References 1. National Library of Medicine, Jan.