It has been postulated that dietary sugar consumption contributes to increased inflammatory processes in humans, and that this may be specific to fructose alone, in sucrose or in high-fructose corn syrup HFCS. Therefore, we conducted a meta-analysis and systematic literature review to evaluate the relevance of fructose, sucrose, HFCS, and glucose consumption for systemic levels of biomarkers of subclinical inflammation. Thirteen studies investigating participants were included in the meta-analysis. The quality of evidence was evaluated using Nutrigrade, and was rated low for these two comparisons. The limited evidence available to date does not support the hypothesis that dietary fructose, as found alone or in HFCS, contributes more to subclinical inflammation than other dietary sugars. Chronic, low-grade inflammation is a key factor in the pathogenesis of cardiovascular disease [ 1 ], and is associated with the risk of developing diabetes [ 2, 3 ], dementia [ 4 ], and depression [ 5 ]. Also, low-grade inflammation is related to a higher risk of all-cause mortality in old age [ 6 ].
Sugar, in its many forms, is a menace. In , the forward-thinking Nancy Appleton wrote a book entitled Lick the Sugar Habit, implicating sugar in diseases. Today we understand that too much sugar — hiding under many names in endless combinations of glucose and fructose — causes a host of health problems, including PAIN. People with diagnosed diabetes are nearly twice as likely to have arthritis, indicating a diabetes-arthritis connection. How does sugar attack our joints? Sugar in its natural form found in most plant foods is designed to give our body energy. By nature, sugar is our friend. But how many of us eat by nature? That raw carrot is the perfect combination of fiber, nutrients, and water relative to its natural sugar content…just what our body needs.
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The pain you feel sugar your stiff, achy joints is your body’s way of letting you know that inflammation exists. Remember that artificial sweeteners are not a health substitute. This works out to be no more than 10 grams per effect. Sorensen et al. Assessment of Quality of Meta-Evidence Diet evaluate the quality of meta-evidence for the association between dietary sucrose, fructose, glucose, and HFCS on subclinical inflammation we applied joint NutriGrade scoring system [ 22 ]. Therefore, there are technically 13 studies included in the review. Results 3. Yaghoobi N. Khan High.